Overdose deaths associated with fentanyl have surpassed those due to heroin or other opioids. In 2022, the DEA seized 50.6 million fentanyl-laced pills masquerading as regulated prescription pills like Xanax or oxycodone — so often times, people don’t even know what they’re taking contains fentanyl. But there isn’t a federal mandate that emergency rooms test specifically for fentanyl.